Our Team
Guiding Light- Dr. Atish Rodge
Dr. Atish Rodge
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Designation
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Founder and Managing Director
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Educational Qualifications
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Graduation: Jagadamba College, Achalpur, Amravati,
Maharashtra, India
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Post Graduation: Shri Shivaji Science College Amravati,
Maharashtra, India
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Ph. D SRTM (Swami Ramanand Tirth University) Nanded,
Maharashtra, India
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Post Doc: Seoul National University, Seoul South Korea
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Patents
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Research Experiences
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National Chemical Laboratory, Pune
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Pharmaceuticals Pvt. Ltd., Mumbai
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Nicolas Primal, Mumbai
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Lupin Research Park, Pune
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National And International Contribution
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He has done brilliant research contribution in the following Publications:
- Bioorganic & Medicinal Chemistry Letters, Volume 18, Issue 24, 15 December 2008, Pages 6357-6361.
- Bioorganic & Medicinal Chemistry Letters, Volume 19, Issue 16, 15 August 2009, Pages 4773-4776.
- Bioorganic & Medicinal Chemistry Letters, Volume 21, Issue 15, 1 August 2011, Pages 4648-4651.
- Bioorganic & Medicinal Chemistry Letters, Volume 21, Issue 19, 1 October 2011, Pages 5812-5817.
- Bioorganic & Medicinal Chemistry Letters, Volume 22, Issue 10, 15 May 2012, Pages 3445-3448.
- Bioorganic & Medicinal Chemistry Letters,Volume 22, Issue 10, 15 May 2012, Pages 3445-3448.
- Bioorganic & Medicinal Chemistry Letters,Volume 22, Issue 20, 15 October 2012, Pages 6385-6390.
- Chem. Pharm. Res., 2010, 2(5):348-355.
- Chem. Pharm. Res., 2011, 3(2):496-505.
- Chem. Pharm. Res., 2011, 3(6):639-648.
- European Journal of Pharmacology, Volume 607, Issues 1 April 2009, Pages 201-212
- Med Chem Res DOI 10.1007/s00044-011-9943-3.
- Med Chem Res DOI 10.1007/s00044-012-0109-8.
- Med Chem Res DOI 10.1007/s00044-012-0144-5.
Poster Presentations
- On Synthesis of Novel Chalcones Derivatives in International conferences
- On Drug Discovery and Nana-technology at Nanded, Maharashtra, India based International Conference
- Presented poster in International Conference on Ionic liquid used in synthesis of Ibuprofen and Green Chemistry and its Perspective for Department of Chemistry, Sant Gadge Baba Amravati University, Amravati (India)
- Presented poster for Department of Chemistry, Sant Gadge Baba Amravati University, Amravati (India) in National Conference on Green Chemistry and its Perspective and Nanotechnology: Application of Heterogeneous Catalyst
- Attended 10th National Symposium in Chemistry at Bangalore (India) based center of Indian Institute of Science on on Green Chemistry (Feb 2008)
- Was an outstanding participant of the 6th International Symposium, made poster on Catalysis in Multiphase Reactor (CAMURE)
- Also participated in 5th International Symposium, which was organized by the National Chemical Laboratory (India) in January 2007, there he presented poster on Catalysis in Multifunctional Reactor (ISMR).
Work Experiences in Association:
Name
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Details
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Dr. Sarala Balachandran
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Project Director, OSDD Unit Council of Scientific and
Industrial Research, Anusandhan Bhawan, Rafi Marg, New
Delhi-110001
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Dr. Ram Vishwakarma
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Director CSIR- Indian Institute of Integrative Medicine, Canal
Road, Jammu- 180 001
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Dr. Goverdhan Mehta,
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Dr. Atish had several Scientific meetings with him
He is National Research Professor in School of Chemistry,
University of Hyderabad, Hyderabad 500 046, India
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Dr. R. A. Mashelkar
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Currently working as the Director General of the Council of
Scientific and Industrial Research.
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Dr, S. S. Joshi
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Scientist E, Process Development Department, National Chemical
Laboratory, Pune
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Dr. Sandip Bharate
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Senior Scientist of Medicinal Chemistry Division and Assistant
Professor (Chemical Sciences), AcSIR, CSIR- Indian Institute of
Integrative Medicine, Canal Road, Jammu- 180001
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Our Inspiring Director- Dr. Girish D. Hatnapure
Dr. Girish D. Hatnapure
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Designation
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Director (R&D) at Olympus Chemicals and Fertilizers
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Educational Qualifications
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Current Responsibility
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Experience
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Before joining our company, as a Research Associate, he
has worked for over 7 years in Novel Drug Discovery and
Development (NDDD) at Lupin (Pune, India)
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Also worked as project assistant at National Chemical
Laboratory, Pune
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Has his own two patents and over 15 publications
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Outline of Experience
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Over 8 years of experience in synthetic medicinal
chemistry, R&D and impurity profile in research institutes &
pharmaceutical industry of India
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During his years of experience, he has worked on different
tasks and various organic reaction
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Successfully handled the multiple synthetic reagents and
purification technique
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Gained expertise in handling multistep synthesis and
synthetic compound characterization using NMR (Proton and 2D)
HPLC and Mass (LCMS).
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Regularly participates in designing novel drug molecule
(New chemical entities) and their synthetic strategies
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Holds rich experience in synthetic process development of
lead molecule.
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Played crucial research role in following Publications-
- Bioorganic & Medicinal Chemistry Letters, 22, 2012, 6385-6390.
- Chem. Pharm. Res., 3, 2011, 639-648.
- Chem. Pharm. Res., 2, 2010, 348-355.
- Medicinal Chemistry Research, DOI 10.1007/s00044-013-0651-z
- Medicinal Chemistry Research, 22, 2013, 1480-1487
- Medicinal Chemistry Research, 22, 2013, 1450-1455
- Bioorganic & Medicinal Chemistry Letters, 22, 2012, 6611-6615.
- Bioorganic & Medicinal Chemistry Letters, 22, 2012, 3445-3448.
- Medicinal Chemistry Research, 21, 2012, 4252-4260.
- Bioorganic & Medicinal Chemistry Letters, 22, 2012, 6385-6390.
- Bioorganic & Medicinal Chemistry Letters, 21, 2011, 4648-4651.
- Chem. Pharm. Res., 3, 2011, 496-505.
He has helped in presenting effective Posters-
- Poster presentation on Synthesis of novel Chalcone derivative
- Poster presentation on Nanotechnology: Application of Heterogeneous Catalyst along with assistance of Mr. G. D. Hatnapure, Mr. H. Rodge, Mr. R. P. Jumde, Mr. M. W. Bhade, Mr. A. P. Keche, Mr. S. T. Bhoge, Mr. M.J. Pawar and Dr. P.R. Padole in National Conference on Green Chemistry and its Perspective (11-12 Feb-2008), Department of Chemistry, Sant Gadge Baba Amravati University, Amravati, India.
- Also presented poster in International Conferences on Drug Discovery and Nano-technology (26-27 Jan-2008), Nanded, Maharashtra India in association with Mr. Atish Rodge, Mr. Ravindra Jumde and Mr. Ashish Keche.
Our Backbone- Dr. Ashish P. Keche
Dr. Ashish P. Keche
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Designation
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Director (R&D) at Olympus Chemicals and Fertilizers
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Educational Qualifications
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Work Experience
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Before joining the company, he had over 7 years of working
experience as a research associate in Novel Drug Discovery and
Development (NDDD) research efforts at Lupin (Pune, India). Has
also done brilliant work as a project assistant at National
Chemical Laboratory, Pune
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He owns two patents and more than 15 publications
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Research Experiences
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More than 8 years of research experience in pharmaceutical
industry along with impressive academic achievements
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Experience includes production of various impurities and
also consist of chemistry such as substitution reactions,
coupling reactions, addition reactions, redox reactions,
elimination reactions, protection & deprotection chemistry
and functional group inter conversions
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Holds expertise in different purification techniques such
as recrystallization, column chromatography, precipitation, etc
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Has strong practical hand on cost effective synthesis of
impurities as well as route of selection
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Professional Associations
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Has done work with eminent Indian scientists such as:
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Dr. Ram Vishwakarma (Director CSIR Indian Institute of
Integrative Medicine, Canal Road, Jammu 180 001)
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Dr. Pratap Reddy (Senior Vice President, Macleod Parma,
Andheri, Mumbai, India).
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Dr, R. M. Deshpande (Scientist E, Process Development
Department, National Chemical Laboratory, Pune)
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Dr. Sham Nikam (Vice President, Head Global Discovery and
Chief Scientific Officer, India, Takeda Pharmaceuticals
International GmbH)
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Current Responsibility
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He has done a great
contribution in the following Publications-
- Bioorganic &
Medicinal Chemistry Letters, 22, 2012, 6385-6390.
- Chem. Pharm. Res.,
3, 2011, 639-648.
- Chem. Pharm. Res.,
2, 2010, 348-355.
- Medicinal Chemistry
Research, DOI 10.1007/s00044-013-0651-z
- Medicinal Chemistry
Research, 22, 2013, 1480-1487
- Medicinal Chemistry
Research, 22, 2013, 1450-1455
- Bioorganic &
Medicinal Chemistry Letters, 22, 2012, 6611-6615.
- Bioorganic &
Medicinal Chemistry Letters, 22, 2012, 3445-3448.
- Medicinal Chemistry
Research, 21, 2012, 4252-4260.
- Bioorganic &
Medicinal Chemistry Letters, 22, 2012, 6385-6390.
- Bioorganic &
Medicinal Chemistry Letters, 21, 2011, 4648-4651.
- Chem. Pharm. Res.,
3, 2011, 496-505.
Dr. Ashish P. Keche
has also participated in the following Posters Presentation-
- On Synthesis of
novel Chalcone derivative
- On Nanotechnology:
Application of Heterogeneous Catalyst in association with Mr. H.
Rodge, Mr. A. P. Keche, Mr. M. W. Bhade, Mr. G. D. Hatnapure, Mr. R.
P. Jumde, Mr. S. T. Bhoge, Dr. P.R. Padole and Mr. M.J. Pawar. In
National Conference on Green Chemistry and its Perspective (11-12
Feb-2008), Department of Chemistry, Sant Gadge Baba Amravati
University, Amravati, India.
- Also participated in
poster presentation along with Mr. Girish Hatnapure, Mr. Atish Rodge,
MR. Ashish Keche, Mr Ravindra Jumde on Drug discovery and
Nano-technology, (26-27 Jan-2008) in in International Conference,
Nanded, Maharashtra India.
Our Passionate
Professional- Dr Gopal K. Toradmal
Dr. Gopal K. Toradmal
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Designation
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Research Scientist (R&D) at Olympus Chemicals and
Fertilizers
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Educational Qualifications
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B.Sc. in the year 2006 with 60.16% in Chem, Bot and Micro,
(D.S.M College Parbhani) S.R.T. M. University, Nanded
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M.Sc. in the year 2008 with 7.31 CGPA in Industrial
Chemistry, S. R. T M. University, Nanded.
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Done Ph.D in Organic Chemistry from S. R. T. M University,
Nanded.
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Current Responsibility
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Synthesis, isolation and characterization impurities,
literature search for project development
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Conducting cost effective synthesis
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Research Experiences
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Conducted research during Ph. D on the topic of
Development of an efficient and green protocols for C-C and
CHeteroatom bond formation employing organoboron reagents,
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Has grown under the guidance of Dr. Rajesh H. Tale, who
was Asst. Prof. In the University
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His PhD work resulted in development of new methodologies
for C-halogen bond formation including NIMI (N-iodomorpholinium
salt) assisted Cu-Catalysed ipso-iodination of arylboronic acids
and protocols for green ipso-iodination
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The quality work he has completed is evident by publishing
in varied reputed international journals like RSC Advances,
Tetrahedron Lett. etc. and C-boron coupling (Miyayura borylation)
of aryl bromides and 1,2,3-triazole ligand accelerated C-nitrogen
coupling (Chan-Lam coupling) of isatin.
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Also made novel ligand for Click chemistry Catalysis and
Various New Ligands with excellent efficiency
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Research Contribution
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Suggested Metal free ipso iodination of arylboronic acids
by making use of CTAB/I2 in aqueous media
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Suggedted Organic synthesis facilities that are needed for
reaction at-78 or below temperature, ll types of dry reaction,
hydrogenation reaction pressure reaction, enzymatic reaction,
microwave reaction and varied other types of basic organic
synthesis.
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Suggested Analytical LC_MS for Shimazoo analytical HPLC
for Purity, RT, RRT and RF monitoring, online reaction
monitoring, low % impurities from API, waters preparative HPLC
for isolation of degraded impurities, etc.
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Research report on finished products that are
characterized by 13CNMR, Mass/LC-MS, IR, HNMR, Melting Point,
Purity RT, CHN analysis, RRT and RF
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Our FacilitiesTo easily complete the processing and all other business tasks related to the offered chemical formulations, we have maintained sound facilities. Investing a heavy sum of money, our company has maintained Organic Synthesis Facilities for the following:
- Synthesis of complex organic molecules and several types of organic chemistry reaction
- High pressure reaction, hydrogenation reaction and microwave reaction
- Dry reaction with temperature range 00C to -780C or below.
- Identification & isolation of unknown impurities
- Enzymatic reaction as well as degradation of final API to isolate impurities
Parallel reactions
- Once the products of our company are prepared, quality of them is analyzed in the maintained testing cell. Below mentioned are some of the Analytical Facilities that we own:
- For isolation of organic compound by silica gel column chromatography
- For modern flash chromatography technique with the use of grace or Bio-tage and combi flash technique
- RT/RRT and peak purity confirmation in tandem with the pharmacopeia method or in house method for Shimadzu LC solution HPLC Analysis systems
- For the isolation & identification of unknown impurities, we have Shimadzu LC solution preparative HPLC
- In this cell, Mass and HNMR analysis is also done in association with other FDA approved testing laboratories
Apart from aforesaid facilities, check the below table to know more:
Storage & Packing Facilities
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Spacious storage facilities from room temperature to 0 0C
to -780C.
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In our premise, with proper sealing and safety, solid and
liquid compound are packed in high quality material of high
recovery vial
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Products of sensitive nature are packed in specially
design vial under nitrogen flow and then shipment is made in 0 to
-780C as per requirement.
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Documentation Facilities
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